Ag-Defense Systems Builds a Portable Lab for E. coli and Salmonella

The Peoria-based startup, founded in 2007, is seeking funding to engineer its portable pathogen detector after initial prototype testing.

About Ag-Defense Systems

Published

The standard workflow for detecting a foodborne pathogen like E. coli or Salmonella is not built for speed. It involves collecting a sample, shipping it to a central lab, and waiting days for a result while perishable inventory sits in limbo. Ag-Defense Systems, operating out of Peoria, Illinois since 2007, is engineering a different path. Its bet is a single, portable instrument that combines sample preparation and molecular testing, designed to deliver an answer at the farm gate, the processing plant dock, or the border checkpoint [Ag-Defense Systems].

The technical wedge

The company's proposed wedge is integration. Instead of requiring multiple pieces of lab equipment and trained technicians, the goal is a unified device that handles the entire process from raw sample to diagnostic result. The target pathogens are the usual suspects in food safety crises: E. coli, Salmonella, and Listeria [Ag-Defense Systems]. For buyers in agriculture and food processing, the value proposition is time and location. A negative test could clear a truckload for processing immediately; a positive result could trigger a containment protocol before contaminated product enters a broader supply chain. The company has filed two patents around this technology and completed initial testing on a preliminary prototype [CB Insights] [Ag-Defense Systems].

The team behind the test

The effort is led by founder and CEO Rex Dyer, a scientist with a background in molecular biology and assay development whose career spans academic, industry, and government research settings [ZoomInfo] [LinkedIn, retrieved 2026]. He is joined by President Beth Turnbull, who holds a D.V.M. and Ph.D., bringing veterinary and medical expertise to the table [Ag-Defense Systems]. The company lists several key collaborators, a structure that suggests a research-focused rather than commercial-stage operation. This includes Matthew Stasiewicz, an associate professor of applied food safety at the University of Illinois Urbana-Champaign, and Andrew Berberich, president of Integris Group, LLC [Ag-Defense Systems].

Role Name Key Background / Affiliation
Founder, VP & CEO Rex Dyer, Ph.D. Molecular biology, assay development; experience at Reditus Laboratories, University of Illinois [ZoomInfo] [RocketReach]
President Beth Turnbull, D.V.M., Ph.D. Veterinary and medical sciences [Ag-Defense Systems]
Collaborator Matthew Stasiewicz, Ph.D. Associate Professor of Applied Food Safety, University of Illinois Urbana-Champaign [Ag-Defense Systems]
Collaborator Andrew Berberich President & CEO, Integris Group, LLC [Ag-Defense Systems]

The path to a product

Ag-Defense Systems currently describes itself as seeking funding to engineer a commercial prototype, indicating it is pre-revenue and pre-seed in its commercial journey [Ag-Defense Systems]. The long development timeline since its 2007 founding points to the significant technical hurdles in miniaturizing and ruggedizing laboratory-grade biological assays. The proposed market is vast, covering agricultural producers, food processors, and regulatory points of entry [Ag-Defense Systems]. Success would mean displacing the entrenched, slower lab-service model with a capital equipment sale,a different motion altogether.

The technical breakdown is straightforward: the device must perform nucleic acid extraction, amplification, and detection reliably outside a controlled lab environment. This requires overcoming challenges like sample matrix interference, temperature control for reagents, and minimizing user error. The two filed patents likely address these integration and stabilization problems [CB Insights]. At scale, the failure modes are predictable. Sensor drift in field conditions could lead to false negatives, a catastrophic outcome for food safety. Reagent stability and supply chain logistics become critical operational burdens. Furthermore, achieving regulatory approvals for a diagnostic device used in food commerce would be a multi-year, capital-intensive process separate from the core engineering work.

Sources

  1. [Ag-Defense Systems] About Ag-Defense Systems | https://www.agdefensesystems.com/about-ag-defense-systems.html
  2. [CB Insights] AG Defense Systems - Products, Competitors, Financials, Employees, Headquarters Locations | https://www.cbinsights.com/company/ag-defense-systems
  3. [ZoomInfo] Contact Rex Dyer, Email: d***@agdefensesystems.com & Phone Number | Founder at AG-Defense Systems | https://www.zoominfo.com/p/Rex-Dyer/1221973856
  4. [LinkedIn, retrieved 2026] Matthew Stasiewicz - Associate Professor of Applied Food Safety, University of Illinois at Urbana-Champaign | https://www.linkedin.com/in/mstasiewicz/
  5. [RocketReach] Rex Dyer Email & Phone Number | Ag-Defense Systems, Inc. Founder Contact Information | https://rocketreach.co/rex-dyer-email_22793666

Read on Startuply.vc